Solid phase microextraction technique Keywords: Analyte, affinity, microextraction, SPME, stationary phase. It has been developed for the analysis of volatile and some nonvolatile compounds. In this review, 10 commercially available solid-phase microextraction systems are presented, with special attention to the appraisal of their analytical, bioanalytical, and environmental engineering Apr 21, 1997 · Solid Phase Microextraction: Theory and Practice Janusz Pawliszyn Solid phase microextraction (SPME) is a recently proposed solvent-free sampling and sample preparation technique. Dec 28, 2012 · Understanding Solid-Phase Microextraction: Key Factors Influencing the Extraction Process and Trends in Improving the Technique Sep 1, 2020 · A facile cooling-assisted solid-phase microextraction device for solvent-free sampling of polycyclic aromatic hydrocarbons from soil based on matrix solid-phase dispersion technique Aug 11, 2000 · Solid-phase microextraction (SPME) is a simple and effective adsorption and desorption technique, which eliminates the need for solvents or complicated apparatus, for concentrating volatile or nonvolatile compounds in liquid samples or headspace. It is easy, combining capability with gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), which makes this method fast, reliable, and This book presents detailed descriptions of the most relevant sorbent based and solvent-based microextraction techniques. A rich library of applications has been developed during already 25 years of use in trace analysis laboratories. Feb 4, 2022 · The solid-phase microextraction (SPME), invented by Pawliszyn in 1989, today has a renewed and growing use and interest in the scientific community with fourteen techniques currently available on the LPME, or liquid phase microextraction, is defined as a miniaturized technique derived from liquid–liquid extraction, characterized by its simplicity, rapidity, low cost, and applicability to various compounds, while minimizing organic solvent use and matrix effects. , sampling, extraction, concentration, derivatization, in a single step. Nov 1, 2015 · In this review, we present a brief introduction to the concept of imprinting templates in polymers and how it is achieved in practice, followed by a discussion of how molecularly-imprinted polymers (MIPs) have been used in combination with solid-phase microextraction (SPME). In this technique, the type of fiber coating plays a crucial role for extraction efficiency. This review explores the applications of SPE and solid-phase microextraction (SPME) in LC-MS-based metabolomics. Solid-phase microextraction (SPME) is a sample preparation technique with many applications that is being continuously developed. One of the most widespread SPME Jan 14, 2010 · Solid-phase microextraction (SPME) is a relatively new sampling technique wherein sample extraction and pre-concentration could be achieved in a single step. AI generated definition based on: Analysis of Cosmetic Products, 2007 Feb 6, 2025 · February 06, 2025 / Organomation Solid-Phase Extraction (SPE) and Solid-Phase Micro-extraction (SPME) are two powerful sample preparation techniques widely used in analytical chemistry. The fiber is then thermally desorbed into Jul 1, 2021 · The use of porous materials as sorbents in sample preparation techniques has gained recent scientific attention in the context of developing novel fibers for the Solid-phase microextraction (SPME Aug 4, 2020 · A review of micro-solid-phase extraction techniques and devices applied in sample pretreatment coupled with chromatographic analysis Oct 1, 2021 · Solid-phase microextraction (SPME) is a popular analytical sample preparation technique that meets the requirements of GAC; SPME was developed in the 1990s by Prof. Recent development in solid phase microextraction related techniques is microextraction by packed sorbent (MEPS). These techniques allow for integrating several operations, such as sample collection, extraction, analyte enrichment above t … Jan 1, 2016 · Abstract Solid-phase microextraction (SPME) is an equilibrium-based sample preparation method that permits the integration of sampling, sample clean-up, and preconcentration in a single step. The article covers the evolution of SPME, its various modes, the diverse range of applications across different industries, recent Mar 1, 2019 · Liquid-phase microextraction is a miniaturized form of traditional liquid–liquid extraction in which the extracting organic phase is limited to a few microliters for extraction of target analytes. MEPS is the miniaturization of conventional SPE and can be connected online to GC or LC without any modifications [18 Mar 8, 2023 · Solid-phase microextraction (SPME) is a simple and convenient sample preparation technique that enables automation, miniaturization, high-throughput performance and online coupling with analytical instruments. Aug 25, 2022 · Solid phase microextraction is a quick and easy sample preparation technique that extracts organic analytes from a matrix onto a stationary phase, similar to solid phase extraction. Since its development, the utilization of SPME has addressed the need to facilitate rapid sample preparation and integrate sampling Among these, in-tube solid-phase microextraction (IT-SPME) using capillaries as extraction devices has gained attention as an advanced “green extraction technique” that combines miniaturization, on-line automation, and reduced solvent consumption. While both methods aim to isolate and concentrate analytes from complex matrices, they differ significantly in their approach, applications, and advantages. This review presents an overview of the history of the SPME technique and its early adaptation based on reported patents, followed by some current SPME designs, and intended usage, especially for gas chromatography (GC Oct 11, 2023 · Liquid phase microextraction (LPME) and solid phase microextraction (SPME) are popular extraction techniques for sample preparation due to their green and highly efficient single-step extraction efficiency. Author: Anita Peterson, Ph. With the increasing attention to essential oils, their evaluation and analysis are significant in analytical sciences. Since its proposal at the ends of the 1980s, the technique has been continuously evolving. In this review, starting from a brief description of the recent Jan 17, 2020 · Solid-phase microextraction (SPME) is a sample preparation technique that uses a small amount of extraction phase to extract analytes from the sample matrix under study (Zacharis & Tzanavaras, 2020). Currently available commercial coatings have certain drawbacks that have been overcome by the development of new coatings based on novel materials; these have improved the Solid-Phase Microextraction Solid-phase microextraction (SPME) presents a cornerstone for a new era of solventless extraction, miniaturization, and automation in pharmaceutical analysis. The information about novel methodological and instrumental solutions in relation to different variants of SPE techniques, solid-phase microextraction (SPME), in-tube solid-phase microextraction (IT-SPME), and magnetic solid-phase extraction (MSPE) is presented. Jan 1, 2021 · Solid-phase microextraction (SPME) is a reference technique in the analytical sample preparation context. It can be used for headspace and immersion sampling Nature protocols, 2010 Solid-phase microextraction (SPME) is a sample preparation method developed to solve some of the analytical challenges of sample preparation as well as sample introduction and integration of different analytical steps into one system. Aug 11, 2000 · Abstract Solid-phase microextraction (SPME) is a simple and effective adsorption and desorption technique, which eliminates the need for solvents or complicated apparatus, for concentrating volatile or nonvolatile compounds in liquid samples or headspace. It consists of a fused silica This book offers comprehensive information on the developments and applications of the solid phase microextraction (SPME) technique. However, the addition of an internal standard provides an additional step in sample preparation. SPME represents a quick, sensitive, and economical approach that can be adopted for field work and can be easily integrated with present analytical instrumentation into an automation process. Jan 1, 2012 · This is because a small volume of the extracting phase is being used relative to the sample volume, such as is employed in microextraction [solvent microextraction or solid-phase microextraction (SPME)] or a low sample matrix-extraction phase distribution constant, as is typically encountered in gaseous headspace techniques. This book chapter aims to provide a comprehensive overview of the principles, applications, advancements, and challenges associated with SPME. e. Either from a sample headspace or from immersion into an aqueous sample. Nov 13, 2020 · Several manuscripts in which the greenness of a solid-phase microextraction (SPME) technique was compared to other sample preparation strategies using the Green Analytical Procedure Index (GAPI), a green assessment tool, were reviewed. In addition, the SBSE technique was applied to some drugs in biological samples in combination with GC-MS [17]. . Solid-phase microextraction (SPME) is an appropriate technique for sample preparation that supports automation, a reduction in the analysis time, high throughput performance, and conveniently couples with the analytical instruments. Janusz Pawliszyn, undergoing constant modes and fibers developing year by year (see Fig. Normally, a small amount of extraction phase dispersed on a supporting medium is exposed to the sample for a specic time before its desorption and analysis. Jul 29, 2004 · Abstract Solid-phase microextraction (SPME) is a modern, solvent-free sample preparation technique, commonly used in trace analysis. Aug 1, 2022 · Solid-phase microextraction (SPME) has become a powerful sample preparation technique which allows to efficiently isolate and enrich analytes from complex matrixes. SPME is compatible with analyte separation and detection by gas chromatography and high-performance liquid chromatography, and provides linear Solid-phase microextraction or SPME is a unique solventless sample prep technique. Cucumbers were sampled, d … Jun 20, 2024 · Predicting the bioavailability of polycyclic aromatic hydrocarbons in rhizosphere soil using a new novel in situ solid-phase microextraction technique Hu Cheng a b , Qian Sun c , Yongrong Bian a, Jiangang Han b, Xin Jiang a, Jianming Xue d, Yang Song a Show more Add to Mendeley This book presents detailed descriptions of the most relevant sorbent based and solvent-based microextraction techniques. This technique incorporates sample extraction, concentration, and sample introduction in one step and is fast, requires no solvents, is reusable, and can be adapted to any GC. While in the first decades of SPME evolution, in-fiber and in-tube approaches were extensively used in different application fields, thin-film microextraction emerged in the 2000s as an attempt to This presentation provides an overview of solid phase microextraction (SPME), including its history, basic principles, and applications. These techniques are simple to perform, do not require further concentration steps, are environmentally May 24, 2022 · Solid-phase microextraction (SPME) possesses unique features that allow it to be used in analyses that would not be possible with traditional sample-preparation methods. In the early 1990s, Pawliszyn et al. - Download as a PPTX, PDF or view online for free Aug 15, 2022 · Abstract In this study, a cooling assisted solid-phase microextraction technique (CA-SPME) was proposed and used for identifying volatile and semi-volatile compounds in edible oil innovatively coupled to gas chromatography-mass spectrometry. Jan 18, 2022 · Solid phase microextraction, or SPME, is a fast and versatile sample preparation technique that reduces sample handling and solvent consumption. This technique works by exposing a coated fiber to the headspace of the sample of interest and allowing the volatile compounds to adsorb or absorb onto the fiber coating. Investigations were carried out to determine whether flavor compounds characteristic for fresh cucumbers could be rapidly determined using a solid-phase microextraction (SPME) dynamic headspace sampling method combined with gas chromatography and flame ionization detection. In the case of microextraction by packed sorbent, dispersive solid-phase extraction or matrix solid-phase dispersion and magnetic solid-phase extraction, papers back to 2017 were evaluated, while for micro solid-phase extraction and fabric phase sorptive extraction, 2015 was used as starting year for analysis. Furthermore, flexible probe design enables The Solid Phase Microextraction (SPME) technique was invented by Pawliszyn in 1989 [9]. As a solvent-free sample preparation method, SPME aligns with the principles of green chemistry by eliminating the need for harmful solvents and minimizing waste production. Jun 8, 2020 · A facile cooling-assisted solid-phase microextraction device for solvent-free sampling of polycyclic aromatic hydrocarbons from soil based on matrix solid-phase dispersion technique Sep 1, 2024 · Currently, solid-phase microextraction technology is the focus of sample preparation methods. The simplicity of SPME protocols and extraction devices makes it a uniform platform for analyzing biological samples, either via t … Often, these aspects lead to the development of new approaches for analyte extraction and clean-up involved in the development of better sorbent coating technology for solid phase microextraction and stir bar sorptive extraction. Feb 11, 2025 · This Special Issue, titled “Applications of Solid-Phase Microextraction and Related Techniques”, features three peer-reviewed review articles and nine original research papers from groups worldwide. Numerous advances have Sep 1, 2024 · After recording the results of each approach, the factors affecting the greenness and practicality of solid-phase microextraction techniques and various analysis methods were compared extensively. Currently, solid-phase extraction is more widely used than traditional organic solvent extraction due to its ease of use and lower solvent requirements. Solid-phase microextraction (SPME), is a solid phase extraction technique that involves the use of a fiber coated with an extracting phase, that can be a liquid (polymer) or a solid (sorbent), which extracts different kinds of analytes (including both volatile and non-volatile) from different kinds of media, that can be in liquid or gas phase. The lack of proper chemical bonding of the stationary phase coating with the substrate surface seems to be responsible for the low thermal and chemical stability of conventionally coated fibers, and these Sep 20, 2024 · Despite advancements in the sensitivity and performance of analytical instruments, sample preparation remains a bottleneck in the analytical process. 1) [1]. Apr 15, 2024 · Solid-phase microextraction (SPME) is an innovative technique for extracting low molecular weight compounds (less than 1500 Da) from highly complex matrices, including biological matrices. Solid phase microextraction (SPME) is a related technique that extracts analytes directly from vapors using a coated fiber for analysis by gas chromatography. Its simplicity of use, relatively short sample processing time, and fiber reusability have made SPME an attractive choice for many analytical applications. The major part of this review deals with Nov 1, 2023 · Vacuum-assisted headspace solid-phase microextraction (Vac-HS-SPME) is an emerging sampling technique that enhances the extraction of semi-volatile compounds. Oct 24, 2021 · Solid-phase microextraction (SPME) is a well-established sample-preparation technique for environmental studies. Dec 1, 2024 · The technique of solid phase microextraction (SPME) offers benefits like solvent-free operation, high extraction efficiency, and miniaturization, making it a promising option for on-site sample pretreatment. Among other modern sample preparation techniques, solid-phase microextraction (SPME) is a state-of-the-art, solvent-free technology that was developed by the research group of Pawliszyn [1] in 1989. Solid-phase microextraction (SPME) possesses unique features that allow it to be used in analyses that would not be possible with traditional sample-preparation methods. Mar 2, 2021 · Solid phase microextraction (SPME) is an evolving technique for the extraction of organic compounds from gaseous, aqueous, and solid matrices. Aug 2, 2024 · Therefore, this study provides an overview of different types of hybrid graphene-based materials as well as their applications in crucial miniaturized techniques, focusing on offline methodologies such as stir bar sorptive extraction (SBSE), microextraction by packed sorbent (MEPS), pipette-tip solid-phase extraction (PT-SPE), disposable May 1, 2024 · Solid-phase microextraction (SPME) is a simple, efficient, and solvent-free technique. Green analytical chemistry aims to develop eco-friendly alternatives, and one of the promising techniques in this field is solid phase microextraction (SPME). Jan 13, 2022 · Solid-Phase Microextraction Solid-phase microextraction (SPME) presents a cornerstone for a new era of solventless extraction, miniaturization, and automation in pharmaceutical analysis. Numerous advances have In recent years, major attention has been focused on microextraction procedures that allow high recovery of target analytes, regardless of the complexity of the sample matrices. Dec 1, 2022 · Solid phase microextraction (SPME) is a widely used but still developing method of extraction of the organic compounds present in liquid, gaseous or solid samples. Written by the inventor Jan 11, 2021 · In-tube solid-phase microextraction (IT-SPME) was developed about 24 years ago as an effective sample preparation technique using an open tubular capillary column as an extraction device. SPME solid-phase microextraction is compatible with green analytical Jun 30, 2015 · Solid-phase microextraction (SPME) is a simple, sensitive, rapid and solvent-free technique for the extraction of analytes from gaseous, liquid and solid samples and takes a leading position among microextraction methods. The complexity also increases depending upon the nature The integration of sample preparation with various analytical instruments is most conveniently achieved by using microextraction techniques and/or microdevices. However, the improvement of microextraction techniques, particularly microextraction by packed sorbent (MEPS) and solid-phase microextraction (SPME), completely modified this scenario by introducing unprecedented control over this process. Oct 1, 2019 · Solid phase microextraction (SPME) is a solvent-free, cost-effective, robust, versatile, and high-throughput sample preparation technique. Jan 1, 2024 · Solid-phase microextraction (SPME) has emerged as a powerful analytical technique in sample preparation and extraction. Mar 1, 2023 · Solid phase microextraction (SPME) is a convenient, effective and green sample preparation technique, offering excellent compatibility with different chromatography methods. Moreover, microextraction techniques, for example solid phase microextraction (SPME) and liquid phase microextraction (LPME), which will be discussed below, are considered to be green extraction techniques, owing to the use of very small quantities of solvents of the extraction phase in relation to the volume of the sample or to the solvent Dec 1, 2024 · Solid-Phase Microextraction (SPME) has emerged as a preferred solvent-free technique to address these limitations. However, the process becomes complex while analyzing sample matrices of heterogeneous nature. Feb 4, 2022 · The solid-phase microextraction (SPME), invented by Pawliszyn in 1989, today has a renewed and growing use and interest in the scientific community with fourteen techniques currently available on Jul 1, 2022 · Solid-phase microextraction (SPME) has become a powerful sample preparation technique which allows to efficiently isolate and enrich analytes from complex matrixes. Solid phase microextraction (SPME) is a solvent-free sample preparation technology. SPME requires the appropriate selection of a robust sorbent for successful utilization under variable conditions. Dec 20, 2013 · Solid phase microextraction find increasing applications in the sample preparation step before chromatographic determination of analytes in samples with a complex composition. It integrates the steps of traditional liquid-liquid extraction, i. The handling of an SPME device is simple, and the analysis of volatiles could be easy. SPME has demonstrated its eco-friendly credentials, significantly reducing the reliance on solvents. In this review the use of solid phase microextraction (SPME), microextraction in packed sorbent (MEPS), and stir-bar sorbtive extraction (SBSE) in drug analysis will be discussed. The application of SPME has extended from the headspace extraction of volatile compounds to the capture of active components in living organisms via the direct immersion of SPME probes into the tissue (in vivo SPME). The simplicity of SPME protocols and extraction devices makes it a uniform platform for analyzing biological samples, either via the headspace or in direct immersion mode. Jan 1, 2017 · A novel solid-phase microextraction using coated fiber based sol-gel technique using poly (ethylene glycol) grafted multi-walled carbon nanotubes for determination of benzene, toluene, ethylbenzene and o-xylene in water samples with gas chromatography-flame ionization detector Mar 24, 2023 · The main goal of this paper is to perform a critical review of sample preparation techniques based on solid-phase microextraction for drug detection in therapeutic monitoring situations. The integration of sample preparation with various analytical instruments is most conveniently achieved by using microextraction techniques and/or microdevices. May 23, 2024 · Solid-phase microextraction (SPME) is an innovative technique for extracting low molecular weight compounds (less than 1500 Da) from highly complex matrices, including biological matrices. Sep 1, 2020 · Solid-phase microextraction (SPME), as a solvent-free extraction technique, has won widespread recognition owing to its unique characteristics of integrating sampling, enrichment and sampling introduction into a single step [10]. Oct 1, 2023 · Purge-assisted solid phase microextraction based on activated carbon as a new technique for determination of odorous compounds in drinking water samples In this article, we review recent progress in well-established solid-phase microextraction technique for in vitro and in vivo analyses of various metabolites and drugs in clinical, pharmaceutical, and toxicological applications. The development of biocompatible coatings and the availability of Solid phase microextraction (SPME) is defined as a sample preparation technique that enhances analytical methods by allowing for the extraction of analytes from various matrices, contributing to improved quality control processes in fields like cosmetic analysis. The development of such miniaturised techniques is an important focus area in Green Analytical Chemistry as it allows for the reduction of toxic solvents and hazardous substances and decreases the complexity, cost, and time of analytical procedures. Oct 1, 2021 · The use of porous materials as sorbents in sample preparation techniques has gained recent scientific attention in the context of developing novel fibers for the Solid-phase microextraction (SPME) technique. It integrates all steps of extraction, such as sampling, isolation, and analysis, into a single step. The simplicity of SPME protocols and extraction devices makes it a uniform This Special Issue, titled “Applications of Solid-Phase Microextraction and Related Techniques”, features three peer-reviewed review articles and nine original research papers from groups worldwide. Jan 1, 2025 · Solid-phase microextraction (SPME) is an appropriate technique for sample preparation that supports automation, a reduction in the analysis time, high throughput performance, and conveniently couples with the analytical instruments. Solid-phase extraction sampling is performed using a fiber, housed in a stainless-steel needle, coated with a sorbent phase that can be liquid or solid. Also, microwave field was used for solid sample preparation improvement. Solid-phase microextraction (SPME) is a simple and convenient sample preparation technique that enables automation, miniaturization, high-throughput performance and online coupling with analytical instruments. Based on the principle of adsorption or absorption and desorption, SPME uses a coated fiber or Arrow to concentrate volatile and semivolatile compounds from a sample. Abstract Determination of a broad spectrum of analytes, carried out with analytical instruments in samples with complex matrices, including environmental, biological, and food samples, involves the development of new and selective sorption phases used in microextraction techniques that allow their isolation from the matrix. The use of novel devices, like packed sorbent (in microextraction by packed sorbent, MEPS), fabric phase sorptive extraction media (in fabric phase sorbent extraction Sep 20, 2024 · Moreover, various microextraction techniques such as micro solid-phase extraction, dispersive micro solid-phase extraction, solid-phase microextraction, stir bar sorptive extraction, liquid-phase microextraction, and magnetic bead extraction have been developed to minimize sample size, reduce solvent usage, and enable automation. Solid-phase microextraction (SPME) is a sample preparation technique which utilizes small amounts of an extraction phase for the extraction of target analytes from investigated sample matrices. The technique was developed an alternative to liquid–liquid extraction (LLE) and solid-phase extraction (SPE). One of the most widespread SPME modes, consists of the extraction directly from the headspace (HS) which is equilibrated with the sample. Nov 8, 2017 · In exhaustive techniques, such as liquid–liquid extraction (LLE) or solid-phase extraction (SPE), the phase ratio of extractant to sample is significantly higher than in microextraction approaches, and geometries are more restrictive to ensure the efficient quantitative transfer of analytes. Other techniques such as solid phase extraction (SPE), solid phase microextraction (SPME,) and stir bar solvent extraction (SBSE) were frequently used in liquid sample preparation. Different types of METs based on extraction media are presented in Fig. The most used techniques included liquid-liquid extraction (LLE), solid-phase extraction (SPE), solid-phase microextraction (SPME), dispersive liquid-liquid microextraction (DLLME), microextraction by packed sorbent Nov 1, 2024 · Solid-phase extraction (SPE) has emerged as a well-established and versatile technique for this purpose, offering advantages over other traditional methods like LLE. This is a fast and solvent-free or very small amount of solvent used, adsorption/desorption technique. SPME (Solid Phase Microextraction) is the highly popular solventless and a true green analysis extraction technique. SPME uses a polymer-coated fiber to concentrate volatile and semi-volatile organics in one extraction step. SPME dramatically reduces the need for organic solvents, aligning with green chemistry principles and contributing to environmental sustainability. D. AI generated definition based on: Journal of Chromatography B, 2014 Mar 24, 2023 · The main goal of this paper is to perform a critical review of sample preparation techniques based on solid-phase microextraction for drug detection in therapeutic monitoring situations. In this sense, HS-SPME provides one of the best platforms for sample preparation, especially Oct 1, 2012 · Solid-phase microextraction (SPME) is a relatively new sample extraction technique — first described in the 1990s by Pawliszyn (1,2) — that brings some unique capabilities to bear on the chromatographic analysis of dilute solutions in difficult matrices, both liquid and gaseous. Feb 4, 2022 · The solid-phase microextraction (SPME), invented by Pawliszyn in 1989, today has a renewed and growing use and interest in the scientific community with fourteen techniques currently available on the Feb 11, 2025 · This Special Issue, titled “Applications of Solid-Phase Microextraction and Related Techniques”, features three peer-reviewed review articles and nine original research papers from groups worldwide. Different liquid-phase Application of solid-phase microextraction (SPME) technology. 2. In addition, the SPME has also been reported in research related to microorganisms, environmental factors, and medical diagnosis. SPME has been widely applied to the sampling We would like to show you a description here but the site won’t allow us. Oct 1, 2012 · Solid-phase microextraction (SPME) is a relatively new sample extraction technique — first described in the 1990s by Pawliszyn (1,2) — that brings some unique capabilities to bear on the chromatographic analysis of dilute solutions in difficult matrices, both liquid and gaseous. [9] Solid phase microextraction (SPME) is a solvent-free sample preparation technique that uses coated fibers to extract analytes of interest from a sample before analysis by GC or HPLC. The lack of proper chemical bonding of the stationary phase coating with the substrate surface seems to be responsible for the low thermal and chemical stability of conventionally coated fibers, and these lead to An alternative technique to liquid–liquid extraction and SPE is the solid-phase microextraction (SPME). This includes solid-phase microextraction, matrix solid-phase dispersion microextraction, dispersive micro solid-phase extraction, and miniaturized solid-phase extraction. first proposed SPME as a sample preparation technique Solid phase microextraction (SPME) has emerged as a versatile sample preparation technique for the preconcentration of a broad range of compounds with various polarities, especially in environmental studies. Sep 29, 2023 · Solid-phase microextraction (SPME) is a sample preparation technique which utilizes small amounts of an extraction phase for the extraction of target analytes from investigated sample matrices. This paper reviews selected theoretical and practical aspects of the SPME method used for the isolation and preconcentration of impurities, food constituents, additives and Jan 11, 2024 · Headspace solid-phase microextraction (HS-SPME) is a convenient and solvent-free sample preparation technique that enables the extraction of analytes with minimal matrix interference. Furthermore, flexible probe design enables SPME to be Microextraction In subject area: Chemistry Solid phase microextraction (SPME) is defined as an inexpensive, solvent-free technique that facilitates the extraction and preconcentration of analytes from various samples using a microfiber coated with a proper sorbent. Oct 24, 2019 · Solid-phase microextraction (SPME), an emerging sample preparation technique that integrates sampling, extraction, concentration, and sample introduction into one step, has gained wide acceptance in various research fields, including in the determination of endogenous compounds. Moreover, SPME reduces analysis times, as well as solvent and disposal costs. This technique has been used in food science research, botanical component analysis, and pharmaceutical studies. There are some reviews in this field that consider SPME and/or MIP [1], [2]. Dec 26, 2019 · Solid‐phase microextraction (SPME) is a simple, fast, and efficient sample preparation technique that eliminates the need for solvents and integrates sampling, isolation, and enrichment in one Nov 2, 2012 · Solid-phase microextraction (SPME) is a relatively new sample extraction technique — first described in the 1990s by Pawliszyn (1,2) — that brings some unique capabilities to bear on the chromatographic analysis of dilute solutions in difficult matrices, both liquid and gaseous. The first part of the book briefly introduces readers to the fundamentals of SPME, while subsequent sections describe the applications of SPME technique in detail, including environmental analysis (air, water, soil/sediments), food analysis (volatile/nonvolatile Solid-phase microextraction (SPME) is a new and effective sample preparation technique. These techniques allow for integrating several operations, such as sample collection, extraction, analyte enrichment above the detection limit of a given measuring instrument and the isolation of analytes from sample Apr 3, 2020 · METs Based on Solid Phase METs with a solid-phase basis include solid-phase microextraction (SPME), in-tube SPME, the needle trap device (NTD), thin-film microextraction (TFME), and fabric phase sorptive extraction (FPSE) [3, 11]. Mar 1, 2019 · Solid-phase microextraction is a well-established green solvent free extraction technique with a large number of applications in different fields such as food, forensic, biomedical, and the environment. Fibers and capillary tubes coated with an appropriate stationary phase are usually used for SPME, but alternative microextraction techniques are also used. SPME was invented in 1990 as a simple, solvent-free technique for isolating and concentrating analytes from samples. Moreover, various microextraction techniques such as micro solid-phase extraction, dispersive Jul 8, 2005 · A sensitive solid-phase microextraction and gas chromatography-pulsed flame photometric detection technique was developed to quantify volatile sulfur compounds in wine. Enhanced Sorptive Extraction by TF-SPMEMiniaturized and solventless sorptive extraction techniques like stir bar sorptive extraction (SBSE) and solid phase microextraction (SPME) have become common choices for sample extraction techniques in the past few decades. Apr 22, 2005 · Solid-phase microextraction (SPME) as a sample preparation and extraction technique is no exception with internal standardisation often used for quantification, particularly when analysing complex samples. It has a wide range of applications in various types of analysis including pharmaceutical, clinical, metabolomics and proteomics. Microextraction techniques allow for less consumption of solvent, reagents, and packing materials, and small sample volumes can be used. Jun 20, 2024 · MeSH terms Animals Biological Availability Environmental Monitoring / methods Lolium Oligochaeta Polycyclic Aromatic Hydrocarbons* / analysis Rhizosphere* Soil Pollutants* / analysis Soil* / chemistry Solid Phase Microextraction* / methods May 2, 2024 · Abstract Solid phase microextraction (SPME) has emerged as a versatile sample preparation technique for the preconcentration of a broad range of compounds with various polarities, especially in environmental studies. Solid Phase Microextraction (SPME) Solid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. This technique has been developed to combine sampling and sample preparation in one step. Jan 1, 2020 · Solid phase microextraction (SPME) is a modern, non-exhaustive sample preparation technique, which has integrated sampling, preconcentration, and extraction into a single step and the trapped analytes can be directly introduced to analytical instruments like chromatographic systems. This technique offers several advantages over traditional methods like liquid-liquid extraction (LLE) and solid-phase extraction (SPE), including automation, rapid sample processing, and reduced solvent usage. The one extra step of pulling vacuum from the sampling vial pre-equilibrium increases the concentration of semi-volatiles in the headspace and allows for faster extraction times. Aug 22, 2024 · Honeycomb-like triazine-bsased conjugated microporous polymers exhibiting simultaneous and ultrasensitive detection of fifteen polycyclic aromatic hydrocarbons using solid-phase microextraction technique. IT-SPME is useful for micro-concentration, automated sample cleanup, and rapid online analysis, and can be used to determine the analytes in complex matrices simple sample processing methods such as direct Dec 20, 2013 · Solid phase microextraction find increasing applications in the sample preparation step before chromatographic determination of analytes in samples with a complex composition. The principle of SPME involves the equilibration of the analytes between a polymeric phase, generally coated onto a fiber, and the sample matrix. Abstract Solid-phase microextraction (SPME) possesses unique features that allow it to be used in analyses that would not be possible with traditional sample-preparation methods. Jan 1, 2016 · Solid-phase microextraction (SPME) is an equilibrium-based sample preparation method that permits the integration of sampling, sample clean-up, and preconcentration in a single step. Jan 1, 2020 · Solid phase microextraction (SPME) is a solvent-free, cost-effective, robust, versatile, and high-throughput sample preparation technique. Solid-phase microextraction (SPME) is a technique developed for the rapid pretreatment of laboratory samples and on-site samples [4 –6]. Despite the advantages of solid-phase microextraction, liquid-phase microextraction was also rapidly become a popular method due to its unique characteristics. Solid-phase microextraction (SPME) is both simple and effective, enabling miniaturization, automation and high-throughput performance. Aug 2, 2025 · In-tube solid-phase microextraction with a dummy molecularly imprinted monolithic capillary coupled to ultra-performance liquid chromatography-tandem mass spectrometry to determine cannabinoids in plasma samples Mar 1, 2020 · In the last decade, the development and adoption of greener and sustainable microextraction techniques have been proved to be an effective alternative to classical sample preparation procedures.